Pediatric Grand Rounds

1. Discuss the basic brain profile in DS, in relation to behavior specifically;
2. Explain behavior principles and strategies that are effective in DS; and
3. Discuss the concepts of the neuroscience of DS and behavior management in DS in a manner that is flexible and can be applied to a wide variety of situations.

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Physicians

Indiana University School of Medicine designates this enduring activity for a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

References for this presentation:

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• Brickell, C., & Munir, K. (2008). Grief and its complications in individuals with intellectual disability. Harvard Review of Psychiatry, 16(1), 1-12.
• Buckley, S., & Bird, G. (2002). Cognitive development and education: Perspectives on Down syndrome from a twenty-year research programme. In M. Cuskelly, A. Jobling, & S. Buckley, Down Syndrome Across the Lifespan (pp. 66-80). London: Whurr Publishers.
• Bull, M. (2011). Committee on Genetics: Health Supervision of Children with Down syndrome. Pediatrics, 128, 393-406.
• Capone, G., Grados, M., Kaufmann, W., Bernad-Ripoli, S., & Jewell, A. (2005). Down syndrome and comorbid autism-spectrum disorder: Characterization using the aberrant behavior checklist. American Journal of Medical Genetics Part A, 134(4), 373-380.
• Centers for Disease Control and Prevention. (2014). www.CDC.gov. Retrieved September 25, 2014, from www.cdc.gov/features/dsdownsyndrome
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• Kumin, L. (2006). Speech intelligibility and childhood verbal apraxia in children with Down syndrome. Down Syndrome Research and Practice(10), 10-22.
• Loft, I. (2012). Neurological phenotypes for Down syndrome across the lifespan. Progress in Brain Research(197), 101-121.
• Lott, I., & Dierssen, M. (2010). Cognitive deficits and associated neurological complications in individuals with Down's syndrome. The Lancet, 9, 623-633.
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• Su, C., Wu, Y., & Chen, C. (2008). The role of cognition and adaptive behavior in employment of people with mental retardation. Research in Developmental Disabilities, 29(1), 83-95.
• Winders, P. (1997). Gross motor milestone statistics; In: Gross motor skills in children with Down syndrome: A guide for parents and professionals. Baltimore, MD: Woodbine House.

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