Pediatric Grand Rounds

1. Discuss the basic brain profile in DS, in relation to behavior specifically;
2. Explain behavior principles and strategies that are effective in DS; and
3. Discuss the concepts of the neuroscience of DS and behavior management in DS in a manner that is flexible and can be applied to a wide variety of situations.

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Physicians
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References for this presentation:

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• Brickell, C., & Munir, K. (2008). Grief and its complications in individuals with intellectual disability. Harvard Review of Psychiatry, 16(1), 1-12.
• Buckley, S., & Bird, G. (2002). Cognitive development and education: Perspectives on Down syndrome from a twenty-year research programme. In M. Cuskelly, A. Jobling, & S. Buckley, Down Syndrome Across the Lifespan (pp. 66-80). London: Whurr Publishers.
• Bull, M. (2011). Committee on Genetics: Health Supervision of Children with Down syndrome. Pediatrics, 128, 393-406.
• Capone, G., Grados, M., Kaufmann, W., Bernad-Ripoli, S., & Jewell, A. (2005). Down syndrome and comorbid autism-spectrum disorder: Characterization using the aberrant behavior checklist. American Journal of Medical Genetics Part A, 134(4), 373-380.
• Centers for Disease Control and Prevention. (2014). www.CDC.gov. Retrieved September 25, 2014, from www.cdc.gov/features/dsdownsyndrome
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• Dykens, E. (2007). Psychiatric and behavioral disorders in persons with Down syndrome. Mental Retardation and Developmental Disabilities Research Reviews, 13(3), 272-278.
• Feeley, K., & Jones, E. (2006). Addressing challenging behaviour in children with Down syndrome: The use of applied behaviour analysis for assessment and intervention. Down Syndrome Research and Practice, 11(2), 64-77.
• Fidler, D. (2006). The emergence of a syndrome specific personality-motivation profile in young children with Down syndrome. In J. &. Rondal, Down syndrome Neurobehavioral Specificity. Hoboken, NJ: Wiley.
• Fidler, D., & Nadel, L. (2007). Education and Children with Down Syndrome: Neuroscience, Development, and Intervention. Mental Retardation and Developmental Disabilties Research Reviews(13), 262-271.
• Gunn, P. &. (1991). Down syndrome temperament: The stereotype at middle childhood and adolescence. International Journal of Disability, Development, and Education(38), 59-70.
• Howlin, P., Wing, L., & Gould, J. (2008). The recognition of autism in children with Down syndrome- Implications for intervention and some speculations about pathology. Developmental Medicine and Child Neurology, 37(5), 406-414.
• Kumin, L. (1996). Speech and language skills in children with Down syndrome. MRDD Research Reviews, 2, 109-115.
• Kumin, L. (2006). Speech intelligibility and childhood verbal apraxia in children with Down syndrome. Down Syndrome Research and Practice(10), 10-22.
• Loft, I. (2012). Neurological phenotypes for Down syndrome across the lifespan. Progress in Brain Research(197), 101-121.
• Lott, I., & Dierssen, M. (2010). Cognitive deficits and associated neurological complications in individuals with Down's syndrome. The Lancet, 9, 623-633.
• Roizen, N. (2003). Down's syndrome. The Lancet, 361(9365), 1281-1289.
• Su, C., Wu, Y., & Chen, C. (2008). The role of cognition and adaptive behavior in employment of people with mental retardation. Research in Developmental Disabilities, 29(1), 83-95.
• Winders, P. (1997). Gross motor milestone statistics; In: Gross motor skills in children with Down syndrome: A guide for parents and professionals. Baltimore, MD: Woodbine House.

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