Cystic Fibrosis Course 11: CF Gene Therapy Part 2

Monday, September 1, 2025, 12:00 AM - Tuesday, August 31, 2027, 12:00 AM

Until recently, research and treatments for cystic fibrosis (CF) targeted symptoms and did not address the root cause. However, since the discovery of cystic fibrosis transmembrane conductance regulator (CFTR), efforts have shifted toward correcting the underlying genetic variants (other wise known as mutations). Although progress has been gradual, advancements in understanding CFTR-related challenges and the emergence of new techniques have paved the way for several clinical trials. These trials aim to evaluate the safety and efficacy of gene therapy, a promising area expected to grow in the coming years.

Gene therapy studies in CF are inherently complex, requiring long-term follow-up and significant commitment from CF healthcare teams, patients and their support network. To support CF healthcare teams in navigating these challenges, this topic is divided into two focused courses.

Course 11 features three modules that address the challenges of informed consent for gene therapy studies and provides team members with tools for talking to people with CF and their families about gene therapy. Additionally, the final module outlining how safety is protected during clinical trials.

1. Explain how safety is monitored during gene therapy studies and practice effective means for obtaining informed consent;
2. Illustrate effective strategies and tools to discuss gene therapy trials with people with CF.

Please visit the IUSM CEHP website, read the provided information, and scroll down to your course to enroll for free.

Launch Date: 09/01/2025

Expiration Date: 8/31/2027

For questions about accessibility or to request accommodations please contact the IUSM CME office at 317-274-0104 or [email protected]. One week advance notice will allow us to provide seamless access. Please ensure to specify the accommodations you need in order to participate.

AMA PRA Category 1 Credits™ (2.00 hours), ABP MOC Part 2 (2.00 hours), ACPE Contact Hours (2.00 hours), ANCC Contact Hours (2.00 hours), Non-Physician Attendance (2.00 hours), Social Work Category I CEU (2.00 hours)

Mitigation of Relevant Financial Relationships

Indiana University School of Medicine, Continuing Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.