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The Young-Jee Kim Lectureship in Rare Diseases presents "Children’s Interstitial and Diffuse Lung Disease: Infancy to puberty and beyond


The Young-Jee Kim Lectureship in Rare Diseases presents

  • Overview
  • Faculty
  • Tests


Date & Location
Wednesday, July 10, 2019, 12:00 AM - Thursday, July 9, 2020, 12:00 AM

Target Audience
Specialties - Emergency Medicine, Hematology, Internal Medicine, Neurology, Psychiatry, Rheumatology, Surgery General

Overview

Pediatric Grand Rounds


Objectives

At the conclusion of this activity, participants should be able to:


  1. Discuss life spectrum lung function concepts;
  2. Describe US chILD Research Network updates;
  3. Review the key chILD disorders; and
  4. Describe scientific activities in child.

Accreditation

Accreditation Statement

In support of improving patient care, Indiana University School of Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians

Indiana University School of Medicine designates this enduring activity for a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

References for this presentation: 

Bibliography

2015 National Health Interview Survey (NHIS) Data, Table 3-1 and Table 4-1. Available from: https://www.cdc.gov/asthma/most_recent_data.htm. Accessed August 25, 2017.

Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med 1995;332:133-8.

Moorman JE, Akinbami LJ, Bailey CM, Zahran HS, King ME, Johnson CA, et al. National surveillance of asthma: United States, 2001-2010. Vital Health Stat 2012;3(35):1-58.

Bui AL, Dieleman JL, Hamavid H, Birger M, Chapin A, Duber HC, et al. Spending on children’s personal health care in the United States, 1996-2013. JAMA Pediatr 2017;171:181-9.

Ralston SL, Lieberthal AS, Meissner HC, Alverson BK, Baley JE, Gadomski AM, Johnson DW, Light MJ, Maraqa NF, Mendonca EA, Phelan KJ, Zorc JJ, Stanko-Lopp D, Brown MA, Nathanson I, Rosenblum E, Sayles S 3rd, Hernandez-Cancio S; American Academy of Pediatrics. Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis. Pediatrics. 2014 Nov;134(5):e1474-502. 

Oksel C, Granell R, Haider S, Fontanella S, Simpson A, Turner S, Devereux G, Arshad SH7, Murray CS, Roberts G, Holloway JW1, Cullinan P, Henderson J, Custovic A; STELAR and Breathing Together investigators. Distinguishing Wheezing Phenotypes from Infancy to Adolescence: A Pooled Analysis of Five Birth Cohorts. Ann Am Thorac Soc. 2019 Mar 19. [Epub ahead of print]

Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT; NIH/NHLBI AsthmaNet. Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation.vJ Allergy Clin Immunol Pract. 2019 Mar;7(3):915-924.e7. 

Bacharier LB, Beigelman A, Calatroni A, et al. Longitudinal phenotypes of respiratory health in a high-risk urban birth cohort. AJRCCM 2018; 1–48.

Castro-Rodriguez JA, Holberg CJ, Wright AL, Martinez FD. A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med 2000; 162:1403.

Chang TS, Lemanske RF Jr, Guilbert TW, et al. Evaluation of the modified asthma predictive index in high-risk preschool children. J Allergy Clin Immunol Pract 2013; 1:152.

Kurukulaaratchy RJ, Matthews S, Holgate ST, Arshad SH. Predicting persistent disease among children who wheeze during early life. Eur Respir J 2003; 22:767.

Hafkamp-de Groen E, Lingsma HF, Caudri D, et al. Predicting asthma in preschool children with asthma-like symptoms: validating and updating the PIAMA risk score. J Allergy Clin Immunol 2013; 132:1303.

van der Mark LB, van Wonderen KE, Mohrs J, et al. Predicting asthma in preschool children at high risk presenting in primary care: development of a clinical asthma prediction score. Prim Care Respir J 2014; 23:52.

Biagini Myers JM, Schauberger E, He H, Martin LJ, Kroner J, Hill GM, Ryan PH, LeMasters GK, Bernstein DI, Lockey JE, Arshad SH, Kurukulaaratchy R, Khurana Hershey GK. A Pediatric Asthma Risk Score to better predict asthma development in young children. J Allergy Clin Immunol. 2018 Dec 7. [Epub ahead of print] PMID: 30554722

Smit HA, Pinart M, Anto´ JM, et al. Childhood asthma prediction models: a systematic review. Lancet Respir Med 2015; 3:973–984.

Castro-Rodriguez JA, Holberg CJ, Wright AL, Martinez FD. A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med 2000; 162:1403-6.

Guilbert TW, Morgan WJ, Zeiger RS, Bacharier LB, Boehmer SJ, Krawiec M,  Larsen G, Lemanske RF, Jr., Liu A, Mauger DT, Sorkness C, Szefler SJ, Strunk RC, Taussig LM, Martinez FD.  Atopic Characteristics of Children with Recurrent Wheezing at High-risk for the Development of Childhood Asthma, J Allergy Clin Immunol. 2004 Dec; 114(6):1282-7 PMID: 15577824.

Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol 2007; 120:S94-138.

Global Strategy for Asthma Managment and Prevention. 2018.] Available from www.ginaasthma.org.

Yoshihara S, Fukuda H, Tamura M, Arisaka O, Ikeda M, Fukuda N, Tsuji T, Hasegawa S, Kanno N, Teraoka M, Wakiguchi H, Aoki Y, Igarashi H, Terada A, Hasegawa M, Manki A. Efficacy and Safety of Salmeterol/fluticasone Combination Therapy in Infants and Preschool Children with Asthma Insufficiently Controlled by Inhaled Corticosteroids. Drug Res (Stuttg). 2016 Jul;66(7):371-6. 

Guilbert TW, Morgan WJ, Zeiger RS, Mauger DT, Boehmer SJ, Szefler SJ, Bacharier LB, Lemanske RF Jr, Strunk RC, Allen DB, Bloomberg GR, Heldt G, Krawiec M, Larsen G, Liu AH, Chinchilli VM, Sorkness CA, Taussig LM, Martinez FD.Long-term inhaled 
corticosteroids in preschool children at high risk for asthma. N Engl J Med. 2006 May 11; 
354(19):1985-97. PMID:16687711

Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, et al. Individualized therapy for persistent asthma in young children. J Allergy Clin Immunol 2016; 138:1608-18 e12.

Zeiger RS, Mauger D, Bacharier LB, Guilbert TW, Martinez FD, Lemanske RF Jr, Strunk RC, Covar R, Szefler SJ, Boehmer S, Jackson DJ, Sorkness CA, Gern JE, Kelly HW, Friedman NJ, Mellon MH, Schatz M, Morgan WJ, Chinchilli VM, Raissy HH, Bade E, Malka-Rais J, Beigelman A, Taussig LM; CARE Network of the National Heart, Lung, and Blood Institute. Daily or intermittent budesonide in preschool children with recurrent wheezing.  N Engl J Med. 2011 Nov 24;365(21):1990-2001.

Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, et al. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA 2015; 314:2034-44.

Rowe BH, Spooner CH, Ducharme FM, Bretzlaff JA, Bota GW. Corticosteroids for preventing relapse following acute exacerbations of asthma.Cochrane Database Syst Rev. 2007 Jul 18;(3):CD000195. 

Stokholm J, Chawes BL, Vissing NH, Bjarnadottir E, Pedersen TM, Vinding RK, et al. Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med 2016; 4:19-26.

Tal A, Levy N, Bearman JE. Methylprednisolone therapy for acute asthma in infants and toddlers: a controlled clinical trial. Pediatrics 1990; 86:350-6.

Csonka P, Kaila M, Laippala P, Iso-Mustajarvi M, Vesikari T, Ashorn P. Oral prednisolone in the acute management of children age 6 to 35 months with viral respiratory infection-induced lower airway disease: a randomized, placebo-controlled trial. J Pediatr 2003; 143:725-30.

Panickar J, Lakhanpaul M, Lambert PC, Kenia P, Stephenson T, Smyth A, et al. Oral prednisolone for preschool children with acute virus-induced wheezing. N Engl J Med 2009; 360:329-38.

 Foster SJ, Cooper MN, Oosterhof S, Borland ML. Oral prednisolone in preschool children with virus-associated wheeze: a prospective, randomised, double-blind, placebo-controlled trial. Lancet Respir Med 2018; 6:97-106.

 Jartti T, Nieminen R, Vuorinen T, Lehtinen P, Vahlberg T, Gern J, et al. Short- and long-term efficacy of prednisolone for first acute rhinovirus-induced wheezing episode. J Allergy Clin Immunol 2015; 135:691-8 e9.

 Lukkarinen M, Lukkarinen H, Lehtinen P, Vuorinen T, Ruuskanen O, Jartti T. Prednisolone reduces recurrent wheezing after first rhinovirus wheeze: a 7-year follow-up. Pediatr Allergy Immunol. 2013 May;24(3):237-43. doi: 10.1111/pai.12046. Epub 2013 Feb 3.


Additional Information

For questions about accessibility or to request accommodations please contact the CME office at 317-274-0104 or [email protected]. One week advance notice will allow us to provide seamless access. Please ensure to specify the accommodations you need in order to participate.


Credits
AMA PRA Category 1 Credits™ (1.00 hours), Non-Physician Attendance (1.00 hours)



In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by the Indiana University School of Medicine (IUSM) must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, and planning committee members participating in an IUSM-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.



Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Robin Deterding, MD
Medical Director
Children's Colorado Innovation Center
Faculty
Salary-co-founder/owner-Triple Endoscopy|Advisory Committee/Board Membership-advisory board member-Boehringer Ingelheim Vetmedica GmbH|Advisory Committee/Board Membership-board member-Now Vitals Inc.|Advisory Committee/Board Membership-board member-Earrables

The Young-Jee Kim Lectureship in Rare Diseases presents "Children’s Interstitial and Diffuse Lung Disease: Infancy to puberty and beyond
Launch Website


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410 W 10th Street, Indianapolis, IN 46202
317-274-0104 | 1-888-615-8013
medicine.iu.edu/education/cme
[email protected]

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